Lead Safe Illinois is a campaign to eliminate lead poisoning in Illinois by raising awareness and advocating for legislation and policy reform to prevent childhood lead poisoning. The campaign works with several lead-safe community initiatives throughout the state to eliminate childhood lead poisoning.

Lead Safe Illinois is convened by the Illinois Lead Safe Housing Task Force and the Loyola University Civitas ChildLaw Center's Policy Institute. The Illinois Lead Safe Housing Task Force, formed in 1997, is an alliance of individuals and public, private, and not-for-profit groups committed to ending childhood lead poisoning that advocates for policy reform, promotes public awareness, and fosters collaborations to achieve its mission. The Task Force is chaired and staffed by the Civitas ChildLaw Center's Policy Institute, a part of Loyola University Chicago School of Law. The Policy Institute promotes child-centered laws, policies and practices, and aims to improve the functioning of the legal, social welfare, juvenile justice, health care and other systems that impact children and families.

In 2006, Lead Safe Chicago and the Civitas ChildLaw Center received the U.S. EPA Children's Environmental Health Excellence Award. Excellence Awards are designed to recognize ongoing and sustainable dedication to, and notable leadership in, protecting children from environmental health risks at the local, regional, national, and international level.